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Entasis Therapeutics
Entasis Therapeutics
(ETTX)
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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Xacduro
Durlobactam
,
Sulbactam
2023-05-23
2033-2035
Respiratory tract infections
,
Urinary tract infections
,
Pneumococcal infections
,
Infectious pregnancy complications
,
Bacterial infections
,
Gonorrhea
,
Intraabdominal infections
,
Bacterial skin diseases
,
Escherichia coli infections
,
Soft tissue infections
,
Bacillary dysentery
,
Surgical wound infection
,
Staphylococcal infections
,
Bacterial endocarditis
,
Bacterial meningitis
,
Salmonella infections
,
Proteus infections
,
Acinetobacter infections
,
Listeriosis
,
Klebsiella infections
,
Meningococcal infections
,
Haemophilus infections
,
Human bites
,
Actinomycosis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Sulbactam
bacterial pneumonia
,
pneumonia
,
infections
,
communicable diseases
,
peritonitis
,
appendicitis
,
wound infection
,
cholecystitis
,
abdominal abscess
,
abscess
,
lung abscess
Durlobactam
renal insufficiency
,
healthy volunteers/patients
,
infections
,
urinary tract infections
,
communicable diseases
,
pyelonephritis
,
acinetobacter infections
,
ventilator-associated pneumonia
,
iatrogenic disease
,
pneumonia
,
bacterial pneumonia
,
bacteremia
Zoliflodacin
healthy volunteers/patients
Etrolizumab
carcinoma
,
merkel cell carcinoma
,
polyomavirus infections
Ademetionine
lung neoplasms
,
healthy volunteers/patients
,
neuroblastoma
,
eye diseases
,
lymphoma
,
neuroendocrine tumors
,
neoplasm metastasis
,
gliosarcoma
,
b-cell chronic lymphocytic leukemia
,
multiple hamartoma syndrome
,
carcinoid tumor
,
aplastic anemia
,
glioma
,
oligodendroglioma
,
ganglioneuroma
,
ganglioglioma
,
neurocytoma
,
cerebellar neoplasms
,
brain neoplasms
,
hepatocellular carcinoma
,
endometrial neoplasms
,
pancreatic neoplasms
,
neuroendocrine carcinoma
,
islet cell carcinoma
,
atopic dermatitis
,
eczema
,
dermatitis
,
hodgkin disease
,
sarcopenia
,
rheumatoid arthritis
,
blast crisis
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
neurofibromatosis 2
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
t-cell lymphoma cutaneous
,
tuberous sclerosis
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
sarcoma
,
hamartoma
,
myeloproliferative disorders
,
essential thrombocythemia
,
thrombocytosis
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
meningioma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
non-hodgkin lymphoma
,
mantle-cell lymphoma
,
colorectal neoplasms
,
kidney neoplasms
,
carcinoma
,
arthritis
,
multiple myeloma
,
plasma cell neoplasms
,
glioblastoma
,
hypertension
,
psoriatic arthritis
,
renal cell carcinoma
,
psoriasis
,
meningitis
,
anemia
,
gout
,
astrocytoma
,
melanoma
,
meningococcal meningitis
,
prostatic neoplasms
,
organ transplantation
,
graft rejection
,
pulmonary arterial hypertension
,
familial primary pulmonary hypertension
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
chronic urticaria
,
urticaria
,
hypersensitivity
,
food hypersensitivity
,
peanut hypersensitivity
,
juvenile arthritis
,
fever
,
hereditary autoinflammatory diseases
,
amyloidosis
,
familial mediterranean fever
,
hyperthermia
,
myalgia
,
tetanus
,
epiglottitis
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
acromegaly
,
depression
,
major depressive disorder
,
depressive disorder
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
chronic hepatitis
,
heart transplantation
,
bone resorption
,
neoplasms
,
leukemia
,
myeloid leukemia
,
kidney transplantation
,
breast neoplasms
,
asthma
,
bcr-abl positive chronic myelogenous leukemia
,
meningococcal infections
,
sclerosis
,
sickle cell anemia
,
liver transplantation
,
multiple sclerosis
,
chronic obstructive pulmonary disease
,
lung diseases
,
obstructive lung diseases
,
gastrointestinal stromal tumors
,
myeloid leukemia acute
,
human influenza
,
macular degeneration
,
lymphoid leukemia
,
iron overload
,
thalassemia
,
alzheimer disease
,
choroidal neovascularization
,
pathologic neovascularization
,
macular edema
,
beta-thalassemia
,
syndrome
,
parkinson disease
,
relapsing-remitting multiple sclerosis
,
dry eye syndromes
,
type 2 diabetes mellitus
,
diabetes mellitus
,
polycythemia vera
,
primary myelofibrosis
,
graft vs host disease
,
polycythemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
myeloid leukemia chronic-phase
,
edema
,
myelodysplastic syndromes
,
preleukemia
,
fatigue
,
wet macular degeneration
,
aspergillosis
,
fibrosis
,
cystic fibrosis
,
allergic bronchopulmonary aspergillosis
,
pulmonary aspergillosis
,
retinal detachment
,
vascular diseases
,
dissociative disorders
,
polypoidal choroidal vasculopathy
,
diabetic retinopathy
,
pneumococcal infections
,
hemochromatosis
,
hemosiderosis
,
philadelphia chromosome
,
heart failure
,
stomach neoplasms
,
osteoporosis
,
ankylosing spondylitis
,
spondylarthritis
,
spondylitis
Doxofylline
tissue adhesions
,
healthy volunteers/patients
Sodium chloride
trismus
,
tetanus
,
diphtheria
,
tetany
,
hiv infections
,
depression
,
depressive disorder
,
heart failure
,
streptococcal infections
,
streptococcus agalactiae
,
sepsis
,
acute kidney injury
,
wounds and injuries
,
toxemia
,
anemia
,
aplastic anemia
,
gout
,
hematologic neoplasms
,
skin neoplasms
,
cutaneous malignant melanoma
,
major depressive disorder
,
suicidal ideation
,
stomach neoplasms
,
bacterial infections
,
gram-positive bacterial infections
,
diabetic nephropathies
,
allergic rhinitis
,
rhinitis
,
allergic rhinitis seasonal
,
uveitis
,
parkinson disease
,
healthy volunteers/patients
,
peritoneal neoplasms
,
intestinal obstruction
,
triple negative breast neoplasms
,
complex regional pain syndromes
,
reflex sympathetic dystrophy
,
somatoform disorders
,
insulinoma
,
hypoglycemia
,
congenital hyperinsulinism
,
nesidioblastosis
,
hyperinsulinism
,
covid-19
,
eosinophilic esophagitis
,
esophagitis
,
sickle cell anemia
,
treatment-resistant depressive disorder
,
meningococcal infections
,
neoplasms
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
osteoporosis
,
melanoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
homozygous familial hypercholesterolemia
,
meningitis
,
meningococcal meningitis
,
cardiovascular diseases
,
carcinoma
,
kidney diseases
,
renal cell carcinoma
,
fibrosis
,
cystic fibrosis
,
prostatic neoplasms
,
stomatitis
,
mucositis
,
pancreatic neoplasms
,
chronic renal insufficiency
,
kidney transplantation
,
graft rejection
,
psoriasis
,
pemphigus
,
rabies
,
encephalitis
,
japanese encephalitis
,
respiratory tract infections
,
pharyngitis
,
common cold
,
metabolic bone diseases
,
bronchitis
,
acute disease
,
pulmonary eosinophilia
,
hepatocellular carcinoma
,
liver neoplasms
,
gastrointestinal stromal tumors
,
atherosclerosis
,
fistula
,
hemorrhage
,
diabetes complications
,
vitreous hemorrhage
,
hypertension
,
essential hypertension
,
metabolic syndrome
,
infections
,
asthma
,
systolic murmurs
,
isolated systolic hypertension
,
neoplasm metastasis
,
whooping cough
,
human influenza
,
diabetes mellitus
,
multiple myeloma
,
plasma cell neoplasms
,
breast neoplasms
,
hypersensitivity
,
left ventricular hypertrophy
,
hypertrophy
,
albuminuria
,
syndrome
,
communicable diseases
,
obesity
,
diabetic retinopathy
,
overweight
,
insulin resistance
,
prehypertension
,
staphylococcal skin infections
,
infectious skin diseases
,
bacterial skin diseases
,
cellulitis
,
angioedema
,
type 2 diabetes mellitus
,
lung diseases
,
macular edema
,
retinal diseases
,
hip osteoarthritis
,
osteoarthritis
,
food hypersensitivity
,
abdominal obesity
,
retinal neovascularization
,
pathologic neovascularization
,
migraine disorders
,
migraine without aura
,
angina pectoris
,
microvascular angina
,
headache
,
migraine with aura
,
health risk behaviors
,
vascular stiffness
Aspartame
hyperlipidemias
,
gastrointestinal stromal tumors
,
anemia
,
iron-deficiency anemia
,
iron deficiencies
,
glioblastoma
,
gliosarcoma
,
lung neoplasms
,
small cell lung carcinoma
,
healthy volunteers/patients
,
leukemia
,
primary myelofibrosis
,
myeloid leukemia acute
,
myeloid leukemia
,
carcinoma
,
hepatocellular carcinoma
,
diarrhea
,
plexiform neurofibroma
,
neurofibromatoses
,
neurofibroma
,
thalassemia
,
iron overload
,
chronic obstructive pulmonary disease
,
obesity
,
triple negative breast neoplasms
,
pre-eclampsia
,
eclampsia
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
lupus nephritis
,
nephritis
,
inflammatory breast neoplasms
,
prostatic neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
hemorrhage
,
wiskott-aldrich syndrome
,
bcr-abl positive chronic myelogenous leukemia
,
metaplasia
,
syndrome
,
hyperlipoproteinemia type ii
,
organ transplantation
,
homozygous familial hypercholesterolemia
,
cryopyrin-associated periodic syndromes
,
myelodysplastic syndromes
,
preleukemia
,
liver transplantation
,
thrombocytopenic purpura idiopathic
,
thrombocytopenic purpura
,
purpura
,
parkinson disease
,
eosinophilia
,
cellulitis
,
juvenile arthritis
,
arthritis
,
hepatitis b
,
hepatitis
,
hepatitis b virus
,
hepatitis a
,
macular edema
,
edema
,
vision disorders
,
low vision
,
pituitary acth hypersecretion
,
acth-secreting pituitary adenoma
,
osteoporosis
,
acute coronary syndrome
,
bronchitis
,
acute disease
,
pulmonary eosinophilia
,
pancreatic neoplasms
,
fistula
,
delirium
,
kidney transplantation
,
asthma
,
hypercholesterolemia
,
cardiovascular diseases
,
atherosclerosis
,
chronic kidney failure
,
kidney diseases
,
thrombocytopenia
,
neoplasms
,
breast neoplasms
,
heart failure
,
renal insufficiency
,
infections
,
dyslipidemias
,
chagas disease
,
chronic renal insufficiency
,
renal dialysis
,
renal replacement therapy
,
drug-related side effects and adverse reactions
,
heart transplantation
,
polycystic kidney diseases
,
autosomal dominant polycystic kidney
,
arthrogryposis
,
fibrosis
,
cystic fibrosis
,
pseudomonas infections
,
type 2 diabetes mellitus
,
diabetes mellitus
,
multiple myeloma
,
plasma cell neoplasms
,
transplantation
,
cytomegalovirus infections
,
communicable diseases
,
melanoma
,
schizophrenia
Cefpodoxime
neoplasms
,
osteomyelitis
,
neuroblastoma
,
diarrhea
,
healthy volunteers/patients
,
hypersensitivity
,
anaphylaxis
,
drug hypersensitivity
,
cephalosporin resistance
,
nephrolithiasis
,
kidney calculi
,
sinusitis
,
rhinosinusitis
,
infections
,
communicable diseases
,
otitis media
,
otitis
,
otitis media with effusion
,
pulmonary infarction
,
soft tissue infections
,
gastroenteritis
,
urinary tract infections
,
microbiota
,
sepsis
,
blister
,
nut hypersensitivity
,
stroke
,
traumatic brain injuries
,
brain injuries
,
aphasia
,
anomia
,
cystitis
Corticorelin
kidney diseases
,
fabry disease
Colimycin
fibrosis
,
cystic fibrosis
,
bronchiectasis
Lactams
healthy volunteers/patients
ETX2514SUL
renal insufficiency
,
infections
,
urinary tract infections
,
communicable diseases
,
pyelonephritis
Trinessa
pneumonia
,
community-acquired infections
,
bacterial pneumonia
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